Ask Difference

Intermolecular Hydrogen Bonding vs. Intramolecular Hydrogen Bonding — What's the Difference?

By Tayyaba Rehman — Published on December 3, 2023
Intermolecular Hydrogen Bonding occurs between separate molecules, while Intramolecular Hydrogen Bonding takes place within a single molecule.
Intermolecular Hydrogen Bonding vs. Intramolecular Hydrogen Bonding — What's the Difference?

Difference Between Intermolecular Hydrogen Bonding and Intramolecular Hydrogen Bonding

ADVERTISEMENT

Key Differences

Intermolecular Hydrogen Bonding and Intramolecular Hydrogen Bonding are essential concepts in chemistry, focusing on how hydrogen bonds form. Intermolecular Hydrogen Bonding pertains to hydrogen bonds formed between separate molecules. Conversely, Intramolecular Hydrogen Bonding concerns hydrogen bonds established within a singular molecule itself.
Tayyaba Rehman
Dec 03, 2023
A fundamental understanding of Intermolecular Hydrogen Bonding is evident in cases like water, where hydrogen bonds exist between water molecules. In contrast, Intramolecular Hydrogen Bonding is evident in compounds like ortho-nitrophenol, where the hydrogen bond forms between different parts of the same molecule.
Tayyaba Rehman
Dec 03, 2023
The implications of Intermolecular Hydrogen Bonding are significant in determining physical properties of substances. For instance, the high boiling point of water is due to Intermolecular Hydrogen Bonding between water molecules. However, Intramolecular Hydrogen Bonding often affects chemical reactivity, as the bond may hinder or promote certain reactions within the molecule.
Tayyaba Rehman
Dec 03, 2023
Both Intermolecular Hydrogen Bonding and Intramolecular Hydrogen Bonding contribute to a substance's characteristics and behavior. Intermolecular bonds influence characteristics like boiling and melting points. In contrast, Intramolecular bonds can impact conformation and reactivity.
Tayyaba Rehman
Dec 03, 2023
From a molecular perspective, Intermolecular Hydrogen Bonding promotes cohesion between molecules, lending stability to the system. In contrast, Intramolecular Hydrogen Bonding might cause a molecule to assume a specific shape or conformation, which might be critical for its function or behavior.
Tayyaba Rehman
Dec 03, 2023
ADVERTISEMENT

Comparison Chart

Occurrence

Between separate molecules
Within a single molecule
Tayyaba Rehman
Dec 03, 2023

Example Compound

Water
Ortho-nitrophenol
Tayyaba Rehman
Dec 03, 2023

Impact on Physical Properties

Influences boiling and melting points
Might not significantly affect physical properties
Tayyaba Rehman
Dec 03, 2023

Influence on Chemical Reactivity

Generally less direct impact
Can affect reactivity due to molecular conformation
Tayyaba Rehman
Dec 03, 2023

Contribution in Molecular Systems

Promotes cohesion between molecules
Determines molecular shape or conformation
Tayyaba Rehman
Dec 03, 2023

Compare with Definitions

Intermolecular Hydrogen Bonding

A bond occurring between different molecules.
The high boiling point of water is attributed to Intermolecular Hydrogen Bonding.
Tayyaba Rehman
Oct 18, 2023

Intramolecular Hydrogen Bonding

Affects the conformation of a molecule.
Ortho-nitrophenol has a specific structure due to Intramolecular Hydrogen Bonding.
Tayyaba Rehman
Oct 18, 2023

Intermolecular Hydrogen Bonding

Influences physical properties like boiling points.
Ethanol's boiling point is raised due to Intermolecular Hydrogen Bonding.
Tayyaba Rehman
Oct 18, 2023

Intramolecular Hydrogen Bonding

Can dictate how a molecule reacts.
Certain reactions are facilitated by the presence of Intramolecular Hydrogen Bonding.
Tayyaba Rehman
Oct 18, 2023

Intermolecular Hydrogen Bonding

Bonds that lend stability between separate entities.
Alcohols often showcase Intermolecular Hydrogen Bonding, influencing their properties.
Tayyaba Rehman
Oct 18, 2023

Intramolecular Hydrogen Bonding

Internal bonding changing molecular behavior.
The stability and shape of some bioactive molecules are due to Intramolecular Hydrogen Bonding.
Tayyaba Rehman
Oct 18, 2023

Intermolecular Hydrogen Bonding

Leads to cohesion in molecular systems.
Intermolecular Hydrogen Bonding in ice structures results in its lower density.
Tayyaba Rehman
Oct 18, 2023

Intramolecular Hydrogen Bonding

A bond taking place within one molecule.
The unique shape of some organic compounds results from Intramolecular Hydrogen Bonding.
Tayyaba Rehman
Oct 18, 2023

Intermolecular Hydrogen Bonding

An interaction not confined to a singular molecule.
The viscosity of certain solutions can be traced back to Intermolecular Hydrogen Bonding.
Tayyaba Rehman
Oct 18, 2023

Intramolecular Hydrogen Bonding

Bonds parts of a single molecule together.
The Intramolecular Hydrogen Bonding in some molecules leads to distinct spectral patterns.
Tayyaba Rehman
Oct 18, 2023

Common Curiosities

Which bonding is responsible for water's high boiling point?

Intermolecular Hydrogen Bonding is responsible for water's high boiling point.
Tayyaba Rehman
Dec 03, 2023

Which type of bonding occurs between different molecules?

Intermolecular Hydrogen Bonding occurs between different molecules.
Tayyaba Rehman
Dec 03, 2023

Does Intramolecular Hydrogen Bonding affect molecular shape?

Yes, Intramolecular Hydrogen Bonding can determine a molecule's shape or conformation.
Tayyaba Rehman
Dec 03, 2023

What dictates the specific conformation of certain organic compounds?

Intramolecular Hydrogen Bonding can dictate the specific conformation of certain compounds.
Tayyaba Rehman
Dec 03, 2023

Are ortho-nitrophenol and water examples of Intramolecular or Intermolecular bonding?

Ortho-nitrophenol showcases Intramolecular Hydrogen Bonding, while water demonstrates Intermolecular Hydrogen Bonding.
Tayyaba Rehman
Dec 03, 2023

How can one identify the presence of Intramolecular Hydrogen Bonding in a molecule?

Intramolecular Hydrogen Bonding can often be identified through spectroscopy and studying molecular structures.
Tayyaba Rehman
Dec 03, 2023

Is Intermolecular Hydrogen Bonding exclusive to water?

No, Intermolecular Hydrogen Bonding is found in various substances, not just water.
Tayyaba Rehman
Dec 03, 2023

Which type of bonding is typically responsible for influencing boiling or melting points?

Intermolecular Hydrogen Bonding typically influences boiling or melting points.
Tayyaba Rehman
Dec 03, 2023

Can a single molecule exhibit Intramolecular Hydrogen Bonding?

Yes, Intramolecular Hydrogen Bonding happens within a single molecule.
Tayyaba Rehman
Dec 03, 2023

Can Intermolecular Hydrogen Bonding contribute to the cohesion of a substance?

Yes, Intermolecular Hydrogen Bonding can promote cohesion between molecules in a substance.
Tayyaba Rehman
Dec 03, 2023

Which type of bonding is more influential in determining a substance's physical properties?

Intermolecular Hydrogen Bonding often plays a more direct role in determining physical properties.
Tayyaba Rehman
Dec 03, 2023

How does Intramolecular Hydrogen Bonding affect chemical reactions?

Intramolecular Hydrogen Bonding can affect reactions by promoting or hindering them due to molecular conformation.
Tayyaba Rehman
Dec 03, 2023

Does Intermolecular Hydrogen Bonding play a role in the viscosity of solutions?

Yes, the viscosity of certain solutions can be influenced by Intermolecular Hydrogen Bonding.
Tayyaba Rehman
Dec 03, 2023

What's the significant difference between Intermolecular and Intramolecular Hydrogen Bonding?

Intermolecular occurs between separate molecules, while Intramolecular happens within a single molecule.
Tayyaba Rehman
Dec 03, 2023

Can Intramolecular Hydrogen Bonding influence the behavior of a molecule?

Yes, Intramolecular Hydrogen Bonding can influence a molecule's behavior, including its reactivity.
Tayyaba Rehman
Dec 03, 2023

Share Your Discovery

Share via Social Media
Embed This Content
Embed Code
Share Directly via Messenger
Link

Author Spotlight

Written by
Tayyaba Rehman
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to askdifference.com. As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.

Popular Comparisons

Featured Comparisons

Trending Comparisons

New Comparisons

Trending Terms