Ask Difference

Gonal F vs. Follistim — What's the Difference?

Edited by Tayyaba Rehman — By Fiza Rafique — Published on January 8, 2024
Gonal F and Follistim are both injectable fertility drugs containing recombinant follicle-stimulating hormone (FSH); the difference primarily lies in their branding and formulation.
Gonal F vs. Follistim — What's the Difference?

Difference Between Gonal F and Follistim


Key Differences

Gonal F and Follistim are renowned names in the world of fertility treatments. Both are medications that contain recombinant follicle-stimulating hormone (FSH). The purpose of both is to stimulate the ovaries to produce multiple eggs, primarily used in assisted reproductive technologies like in vitro fertilization (IVF).
Gonal F's distinction from Follistim is subtle yet essential for patients and healthcare providers. The primary distinction is in the brand and the pharmaceutical companies that produce them. While Gonal F is manufactured by EMD Serono, Follistim is a product of Merck.
When we delve into the administration of these medications, Gonal F and Follistim may have slightly different injection devices. Though both drugs are typically self-administered via subcutaneous injections, their pen devices and storage recommendations can vary.
To sum up, both Gonal F and Follistim play a vital role in fertility treatments, with their primary difference being in branding, the companies that manufacture them, and the specifics of their administration and storage.

Comparison Chart


EMD Serono


Recombinant follicle-stimulating hormone (FSH)
Recombinant follicle-stimulating hormone (FSH)

Injection Device

Specific pen device
Different pen device

Storage Recommendations

According to manufacturer's guidelines
According to manufacturer's guidelines

Primary Use

Stimulate ovaries in fertility treatments
Stimulate ovaries in fertility treatments

Compare with Definitions

Gonal F

Gonal F is a fertility medication used to stimulate the ovaries.
Sarah began her IVF treatment with Gonal F injections.


Follistim contains the recombinant version of follicle-stimulating hormone (FSH).
Understanding that Follistim had the necessary FSH made Jane feel confident about her treatment.

Gonal F

Gonal F contains the recombinant form of follicle-stimulating hormone (FSH).
The doctor informed her that Gonal F was essential for egg development.


Follistim is frequently used in procedures like IVF to promote egg development.
For the best outcome, the clinic recommended Follistim for her IVF regimen.

Gonal F

Gonal F's administration is typically via subcutaneous injection.
She was nervous about the Gonal F shot but found it easier than expected.


Follistim aids in ensuring multiple mature eggs are produced.
With Follistim, Maria was hoping for a good number of mature eggs.

Gonal F

Gonal F is often employed in assisted reproductive technologies.
For her upcoming IVF cycle, Lisa was prescribed Gonal F.


Follistim is an injectable medication utilized for ovarian stimulation.
Karen's doctor switched her from another medication to Follistim for her next cycle.

Gonal F

Gonal F assists in the production of multiple eggs.
With the help of Gonal F, Emily hoped to retrieve multiple eggs this cycle.


Follistim is typically self-administered through subcutaneous injections.
She watched a tutorial on how to properly inject Follistim before her first dose.

Common Curiosities

What is Gonal F primarily used for?

Gonal F is primarily used to stimulate the ovaries in fertility treatments.

Who manufactures Gonal F?

Gonal F is manufactured by EMD Serono.

Why would a doctor prescribe Gonal F over Follistim or vice versa?

Choice can be based on a patient's specific needs, insurance coverage, or the doctor's preference.

Is Follistim similar to Gonal F?

Yes, both Follistim and Gonal F contain recombinant follicle-stimulating hormone (FSH) and are used in fertility treatments.

How are Gonal F and Follistim administered?

Both Gonal F and Follistim are typically self-administered via subcutaneous injections.

Who produces Follistim?

Follistim is produced by Merck.

Are there any significant differences in the effects of Gonal F and Follistim?

Both are used to stimulate the ovaries and contain FSH, but individual responses can vary based on several factors.

Can Gonal F and Follistim be purchased over the counter?

No, both Gonal F and Follistim require a prescription.

How do Gonal F and Follistim work in the body?

Both Gonal F and Follistim introduce FSH to stimulate the ovaries to produce multiple eggs.

How should Gonal F and Follistim be stored?

Both should be stored as per the manufacturer's guidelines, typically in a cool place away from direct sunlight.

Do Gonal F and Follistim have different injection devices?

Yes, Gonal F and Follistim have specific pen devices unique to their brand for administration.

Are there any known side effects of Gonal F and Follistim?

Yes, like all medications, both can have side effects. Patients should consult their physician for detailed information.

Can both Gonal F and Follistim be used in the same treatment cycle?

It depends on the treatment protocol. A doctor will decide the best regimen for a patient.

Are Gonal F and Follistim safe for all women undergoing fertility treatments?

Most women tolerate them well, but individual risks and contraindications should be discussed with a healthcare provider.

Are Gonal F and Follistim the only options for ovarian stimulation?

No, there are other medications available, but Gonal F and Follistim are commonly prescribed.

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Author Spotlight

Written by
Fiza Rafique
Fiza Rafique is a skilled content writer at, where she meticulously refines and enhances written pieces. Drawing from her vast editorial expertise, Fiza ensures clarity, accuracy, and precision in every article. Passionate about language, she continually seeks to elevate the quality of content for readers worldwide.
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.

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