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Condensation vs. Hydrolysis — What's the Difference?

Edited by Tayyaba Rehman — By Fiza Rafique — Published on October 5, 2023
Condensation is a chemical reaction where two molecules combine to form a larger molecule, releasing a smaller molecule like water in the process.
Condensation vs. Hydrolysis — What's the Difference?

Difference Between Condensation and Hydrolysis

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Key Differences

Condensation is a type of chemical reaction in which two smaller molecules join together to form a single, larger molecule. Hydrolysis, conversely, is a chemical reaction where a larger molecule is split into two or more smaller molecules.
Condensation typically releases a small molecule like water or methanol as a byproduct. Hydrolysis uses water to break the bonds within the larger molecule, effectively adding the components of water (H and OH) to the smaller molecules formed.
Condensation is common in the formation of complex organic compounds like proteins and nucleic acids. Hydrolysis plays a significant role in digestion, where complex molecules like proteins and starches are broken down into their constituent parts.
Condensation reactions often require energy input to initiate the process of molecular combination. Hydrolysis usually releases energy, making it an exergonic process, as breaking the bonds in the larger molecule tends to be energetically favorable.
Condensation and hydrolysis are opposite but complementary reactions. They are frequently observed in biological systems where complex molecules are both synthesized (via condensation) and broken down (via hydrolysis) as part of metabolic pathways.
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Comparison Chart

Reaction Direction

Combines smaller molecules
Splits larger molecules

Byproduct

Releases small molecules like water
Consumes water

Energy

Often requires energy input
Usually releases energy

Biological Role

Formation of complex compounds
Breakdown of complex compounds

Examples

Protein synthesis, dehydration
Digestion, saponification

Compare with Definitions

Condensation

Condensation is the combination of two smaller molecules to form a larger one.
The condensation of two amino acids forms a dipeptide.

Hydrolysis

Hydrolysis is common in digestive processes.
The hydrolysis of proteins occurs in the stomach.

Condensation

Condensation is common in organic synthesis.
Condensation is a key step in polymer formation.

Hydrolysis

Hydrolysis often involves the addition of hydrogen and hydroxide ions.
Hydrolysis adds the components of water to the molecules formed.

Condensation

Condensation often releases a small molecule like water as a byproduct.
Condensation reactions in organic chemistry often release water.

Hydrolysis

Hydrolysis usually releases energy.
Hydrolysis reactions are generally exergonic.

Condensation

Condensation can be an endergonic reaction requiring energy.
Some condensation reactions require a catalyst to proceed.

Hydrolysis

Hydrolysis can break covalent bonds.
Hydrolysis can cleave the ester bonds in lipids.

Condensation

Condensation is crucial in biological systems.
Condensation reactions are essential in the biosynthesis of proteins.

Hydrolysis

Hydrolysis is the breakdown of a larger molecule into smaller parts using water.
The hydrolysis of sucrose produces glucose and fructose.

Condensation

Condensation is the change of the physical state of matter from the gas phase into the liquid phase, and is the reverse of vaporization. The word most often refers to the water cycle.

Hydrolysis

Hydrolysis (; from Ancient Greek hydro- 'water', and lysis 'to unbind') is any chemical reaction in which a molecule of water breaks one or more chemical bonds. The term is used broadly for substitution, elimination, and solvation reactions in which water is the nucleophile.Biological hydrolysis is the cleavage of biomolecules where a water molecule is consumed to effect the separation of a larger molecule into component parts.

Condensation

Water which collects as droplets on a cold surface when humid air is in contact with it
The inside of the cab steamed up with condensation

Hydrolysis

The reaction of water with another chemical compound to form two or more products, involving ionization of the water molecule and usually splitting the other compound. Examples include the catalytic conversion of starch to glucose, saponification, and the formation of acids or bases from dissolved ions.

Condensation

The conversion of a vapour or gas to a liquid
The cloud is caused by condensation in the air

Hydrolysis

(chemistry) A chemical process of decomposition involving the splitting of a bond and the addition of the hydrogen cation and the hydroxide anion of water.

Condensation

A concise version of something, especially a text
A readable condensation of the recent literature

Hydrolysis

A chemical process causing the splitting of a chemical bond by the addition of the elements of water. Where the bond which is split is not part of a ring structure, this process causes formation of two compounds from one compound plus water, as in the hydrolysis of the ester bonds of fats during saponification.

Condensation

The act of condensing.

Hydrolysis

A chemical reaction in which water reacts with a compound to produce other compounds; involves the splitting of a bond and the addition of the hydrogen cation and the hydroxide anion from the water

Condensation

The state of being condensed.

Condensation

An abridgment or shortening of something, especially of a written work or speech.

Condensation

The process by which a gas or vapor changes to a liquid.

Condensation

The liquid so formed.

Condensation

(Chemistry) A chemical reaction in which water or another simple substance is released by the combination of two or more molecules.

Condensation

(Psychology) In psychoanalytic theory, the process by which a single symbol or word is associated with the emotional content of several, not necessarily related, ideas, feelings, memories, or impulses, especially as expressed in dreams.

Condensation

The act or process of condensing or of being condensed

Condensation

The state of being condensed.

Condensation

(physics) The conversion of a gas to a liquid.

Condensation

The condensate so formed.

Condensation

(chemistry) The reaction of two substances with the simultaneous loss of water or other small molecule.
Dehydration synthesis

Condensation

(psychology) when a single idea (an image, memory, or thought) or dream object stands for several associations and ideas.

Condensation

The act or process of condensing or of being condensed; the state of being condensed.
He [Goldsmith] was a great and perhaps an unequaled master of the arts of selection and condensation.

Condensation

The act or process of reducing, by depression of temperature or increase of pressure, etc., to another and denser form, as gas to the condition of a liquid or steam to water.

Condensation

A rearrangement or concentration of the different constituents of one or more substances into a distinct and definite compound of greater complexity and molecular weight, often resulting in an increase of density, as the condensation of oxygen into ozone, or of acetone into mesitylene.

Condensation

(psychoanalysis) an unconscious process whereby two ideas or images combine into a single symbol; especially in dreams

Condensation

The process of changing from a gaseous to a liquid or solid state

Condensation

Atmospheric moisture that has condensed because of cold

Condensation

The process or result of becoming smaller or pressed together;
The contraction of a gas on cooling

Condensation

A shortened version of a written work

Condensation

The act of increasing the density of something

Common Curiosities

Do Condensation and Hydrolysis have opposite functions?

Yes, condensation combines molecules, while hydrolysis breaks them apart.

What is released in a Condensation reaction?

Condensation often releases a small molecule like water.

What is Hydrolysis?

Hydrolysis is a chemical reaction that breaks a larger molecule into smaller ones using water.

Is energy released in Hydrolysis?

Hydrolysis usually releases energy.

What is Condensation?

Condensation is a chemical reaction that combines smaller molecules into a larger one.

What role does Hydrolysis play in biology?

Hydrolysis is involved in the breakdown of complex molecules like proteins during digestion.

What is consumed in a Hydrolysis reaction?

Hydrolysis consumes water to break bonds.

What role does Condensation play in biology?

Condensation is involved in the formation of complex organic compounds like proteins.

Are enzymes involved in Condensation and Hydrolysis?

Yes, both reactions often involve enzymes to catalyze the process.

How are Condensation and Hydrolysis related to water?

Condensation releases water, while hydrolysis consumes it.

Is Hydrolysis always exergonic?

Generally, but not always. Some hydrolysis reactions may require energy.

Is energy required for Condensation?

Condensation often requires energy input.

Can Condensation be reversed?

Yes, condensation reactions are often reversible, especially with the addition of water (hydrolysis).

Do both reactions occur in cells?

Yes, both reactions are common in cellular metabolism.

What kinds of bonds can Hydrolysis break?

Hydrolysis can break various types of bonds, including covalent and ester bonds.

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Author Spotlight

Written by
Fiza Rafique
Fiza Rafique is a skilled content writer at AskDifference.com, where she meticulously refines and enhances written pieces. Drawing from her vast editorial expertise, Fiza ensures clarity, accuracy, and precision in every article. Passionate about language, she continually seeks to elevate the quality of content for readers worldwide.
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to askdifference.com. As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.

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