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Urea vs. Urine — What's the Difference?

By Tayyaba Rehman & Fiza Rafique — Updated on September 19, 2023
Urea is an organic compound and a major component in urine, which is a waste fluid produced by the kidneys. While urea is a specific substance, urine is a mixture of urea, water, and other waste products.
Urea vs. Urine — What's the Difference?

Difference Between Urea and Urine


Key Differences

Urea is a specific organic compound with the formula (NH2)2CO, and it is produced in the liver as a result of protein metabolism. Urine, on the other hand, is a complex fluid produced by the kidneys that contains urea among many other dissolved substances, such as salts and creatinine.
Urea is used in various industrial applications, including fertilizers, and can also be synthesized. Urine is a biological waste product expelled by animals, including humans, and is not generally synthesized, although it has some historical and modern applications, like in agriculture as a fertilizer.
Urea can be isolated as a solid or concentrated substance, allowing for easy storage and transport. Urine is a liquid and is usually not stored for long periods, except for medical testing, due to its organic nature and potential for bacterial growth.
Grammatically, "urea" is always used as a singular noun, whereas "urine" can be both a singular and a collective noun, as in the phrase "a sample of urine." Both are commonly used as nouns in scientific and medical contexts.
Both urea and urine are central to the study of human physiology and medicine. Urea levels can be indicative of liver and kidney function, while urine tests are often broader indicators of health, capturing data on hydration, drug use, and other metabolic processes.

Comparison Chart


Specific organic compound
Complex biological fluid


Mixture of urea, water, and other waste products


Industrial and medical
Mainly medical and some agricultural

Grammatical Usage

Singular noun
Singular and collective noun

Associated Sciences

Chemistry, physiology
Physiology, medicine

Compare with Definitions


Urea is a colorless, odorless solid used in fertilizers and cosmetics.
Urea-based fertilizers improve soil quality.


Urine is a waste fluid produced by the kidneys.
A urine test can reveal signs of diabetes.


Urea is a key component of urine that helps in the excretion of waste.
High concentrations of urea in urine suggest dehydration.


Urine is a mixture of urea, water, and other waste products.
Urine composition varies with diet and hydration.


Urea serves as a nitrogenous waste that mammals expel.
Elevated urea levels may signify liver issues.


Urine tests are commonly used in medical diagnostics.
A urine sample is often required for drug tests.


Urea can be synthesized artificially for various applications.
Synthetic urea is commonly used in the textile industry.


Urine is expelled from the body via the urinary tract.
Urinary tract infections can affect the color of urine.


Urea, also known as carbamide, is an organic compound with chemical formula CO(NH2)2. This amide has two –NH2 groups joined by a carbonyl (C=O) functional group.


Urine serves as an indicator for various health conditions.
Dark-colored urine may indicate dehydration.


A water-soluble compound, CO(NH2)2, that is the major nitrogenous end product of protein metabolism and is the chief nitrogenous component of the urine in mammals and certain other animals. Also called carbamide.


Urine is a liquid by-product of metabolism in humans and in many other animals. Urine flows from the kidneys through the ureters to the urinary bladder.


A water-soluble organic compound, CO(NH2)2, formed by the metabolism of proteins and excreted in the urine.


The waste product secreted by the kidneys that in mammals is a yellow to amber-colored, slightly acidic fluid discharged from the body through the urethra.


Any N-substituted derivative of urea, with the general formula (R1R2N)CO(NR3R4).


(physiology) Liquid waste consisting of water, salts, and urea, which is made in the kidneys, stored in the bladder, then released through the urethra.


The chief solid component of mammalian urine; synthesized from ammonia and carbon dioxide and used as fertilizer and in animal feed and in plastics


(archaic) To urinate.


In mammals, a fluid excretion from the kidneys; in birds and reptiles, a solid or semisolid excretion.


To urinate.

Common Curiosities

Are urea and urine the same?

No, urea is a component of urine.

Is urea a liquid?

No, urea is generally a solid or can be concentrated.

Why is urea in urine?

Urea is expelled as waste and is a major component of urine.

Is urine just urea and water?

No, urine also contains other waste products and salts.

Can urea be synthesized?

Yes, urea can be artificially synthesized.

Is urine sterile?

It's generally sterile when it leaves the body but can become contaminated.

Is urea only found in human urine?

No, it's found in the urine of many mammals.

What does a high urea level indicate?

It may indicate kidney or liver issues.

Is urea used in fertilizers?

Yes, it's a common component.

Is urine ever used for anything?

Yes, it has been used in agriculture and some medical tests.

Can you measure urea levels in urine?

Yes, it's a common medical test.

Is urea harmful?

In large amounts, it can be harmful, but it is generally safe in controlled applications.

Is urine always yellow?

No, the color can change based on hydration and health.

Can you have urine without urea?

No, urea is a major component of urine.

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Author Spotlight

Written by
Tayyaba Rehman
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.
Co-written by
Fiza Rafique
Fiza Rafique is a skilled content writer at, where she meticulously refines and enhances written pieces. Drawing from her vast editorial expertise, Fiza ensures clarity, accuracy, and precision in every article. Passionate about language, she continually seeks to elevate the quality of content for readers worldwide.

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