Scleroderma vs. Sarcoidosis — What's the Difference?

Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs. The disease can be either localized to the skin or involve other organs, as well.

Sarcoidosis (also known as Besnier-Boeck-Schaumann disease) is a disease involving abnormal collections of inflammatory cells that form lumps known as granulomata. The disease usually begins in the lungs, skin, or lymph nodes.

A pathological thickening and hardening of the skin.

A disease of unknown origin that is characterized by the formation of granulomatous lesions especially in the lungs and lymph nodes of the chest and trunk, and less often in the skin, eyes, and other organs, and that if untreated may lead to chronic illness and organ damage. Also called sarcoid.

(medicine) A chronic systemic autoimmune disease characterized by hardening the skin or other organs through excessive deposits of collagen.

(medicine) A multisystem disorder characterized by granulomas.

A disease of adults, characterized by a diffuse rigidity and hardness of the skin.

A chronic disease of unknown cause marked by the formation of nodules in the lungs and liver and lymph glands and salivary glands

An autoimmune disease that affects the blood vessels and connective tissue; fibrous connective tissue is deposited in the skin

Genus of poisonous fungi having hard-skinned fruiting bodies: false truffles