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Niacinamide vs. Nicotinamide — What's the Difference?

By Tayyaba Rehman — Updated on August 19, 2023
Niacinamide and nicotinamide are synonymous terms referring to the amide form of vitamin B3, used in skincare and health supplements.
Niacinamide vs. Nicotinamide — What's the Difference?

Difference Between Niacinamide and Nicotinamide

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Key Differences

Niacinamide and nicotinamide both represent the same chemical compound, which is the amide form of vitamin B3. They are interchangeable names for the molecule that plays a critical role in cellular energy production in the body. Both terms describe a compound that is vital for numerous biological processes, including the conversion of food into energy.
Niacinamide and nicotinamide are commonly found in skincare products due to their numerous benefits for the skin. Both names refer to a substance that can help reduce the appearance of fine lines, enlarged pores, and uneven skin tone. They are favored ingredients in cosmetics due to their anti-inflammatory properties and ability to boost the skin's natural barrier.
Niacinamide and nicotinamide, when found in supplements, support overall health, particularly metabolic function and DNA repair. Both terms denote a nutrient that assists enzymes in the release of energy from carbohydrates, fats, and proteins. Additionally, they play a role in cell signaling and DNA repair, offering numerous health benefits.
In the context of skincare and health supplements, there's no distinction between niacinamide and nicotinamide. They are identical in chemical structure and function. So, whether a product label mentions niacinamide or nicotinamide, it refers to the same beneficial compound.

Compare with Definitions

Niacinamide

A molecule that supports DNA repair in cells.
Niacinamide plays a role in preventing DNA damage and mutations.
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Nicotinamide

A nutrient assisting in metabolic functions.
Nicotinamide is vital for the metabolism of fats, carbohydrates, and proteins.

Niacinamide

A compound that assists in cellular energy production.
The body uses niacinamide to convert food into energy.

Nicotinamide

A compound that plays a role in cell signaling.
Nicotinamide is integral for proper cellular communication.

Niacinamide

A substance that can reduce skin inflammation.
Niacinamide serums can help calm redness in irritated skin.

Nicotinamide

A molecule beneficial for skin barrier enhancement.
Using a nicotinamide-infused moisturizer can improve skin hydration and barrier function.

Niacinamide

The amide form of vitamin B3.
Niacinamide can be found in many over-the-counter vitamin supplements.

Nicotinamide

The amide derivative of niacin or vitamin B3.
Nicotinamide is essential for various enzymatic reactions in the body.

Niacinamide

A beneficial ingredient in skincare products.
Niacinamide is praised for its ability to minimize pores.

Nicotinamide

A component in skincare known for anti-aging properties.
Many anti-aging creams contain nicotinamide to target wrinkles.

Niacinamide

The amide of niacin (nicotinic acid), called also nicotinamide. It was at one time called vitamin B3, and can function to relieve nicotinic acid deficiency. Chemical formula C6H6N2O, chemically it is 3-pyridinecarboxamide.

Nicotinamide

Niacinamide or nicotinamide (NAM) is a form of vitamin B3 found in food and used as a dietary supplement and medication. As a supplement, it is used by mouth to prevent and treat pellagra (niacin deficiency).

Niacinamide

(organic compound) The amide of niacin.

Nicotinamide

The amide of nicotinic acid (or niacin).

Common Curiosities

Which term, niacinamide or nicotinamide, is more common in skincare?

Both terms are used interchangeably, but niacinamide might be slightly more prevalent on skincare product labels.

Do niacinamide and nicotinamide serve the same function in the body?

Yes, both niacinamide and nicotinamide play crucial roles in cellular energy production, DNA repair, and other metabolic processes.

Are the benefits of niacinamide and nicotinamide the same in skincare?

Absolutely, since niacinamide and nicotinamide are synonymous, they offer identical benefits in skincare, such as reducing inflammation and improving skin barrier function.

Is niacinamide the same as nicotinamide?

Yes, niacinamide and nicotinamide refer to the same chemical compound, the amide form of vitamin B3.

Can I replace niacinamide with nicotinamide in a product's ingredient list or vice versa?

Yes, since they refer to the same compound, you can use either term interchangeably.

How do niacinamide and nicotinamide benefit the skin?

Both niacinamide and nicotinamide offer anti-inflammatory properties, reduce the appearance of fine lines, and help strengthen the skin's natural barrier.

Do niacinamide and nicotinamide have the same side effects?

Since they are the same compound, any side effects associated with one would also be associated with the other.

Can I find both niacinamide and nicotinamide in vitamin supplements?

Yes, whether labeled as niacinamide or nicotinamide, it's the same beneficial compound in vitamin supplements.

Is there any difference in the chemical structure of niacinamide and nicotinamide?

No, niacinamide and nicotinamide have the same chemical structure: C₆H₆N₂O.

Is one term, either niacinamide or nicotinamide, more scientifically accurate?

No, both terms are scientifically accurate and represent the same compound. The choice of term is often a matter of preference.

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Author Spotlight

Written by
Tayyaba Rehman
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to askdifference.com. As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.

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