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Neurilemma Sheath vs. Myelin Sheath — What's the Difference?

By Tayyaba Rehman — Published on December 1, 2023
Neurilemma Sheath is the outermost layer of Schwann cells surrounding a nerve fiber. Myelin Sheath is an insulating layer formed by glial cells around nerve fibers.
Neurilemma Sheath vs. Myelin Sheath — What's the Difference?

Difference Between Neurilemma Sheath and Myelin Sheath

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Key Differences

Neurilemma Sheath is the outer layer of Schwann cells on peripheral nerves. Myelin Sheath, on the other hand, is made by oligodendrocytes in the CNS and Schwann cells in the PNS.
The Neurilemma Sheath plays a role in nerve regeneration. The Myelin Sheath primarily provides insulation and increases nerve impulse speed.
Neurilemma Sheath is present in all peripheral nerve fibers. Myelin Sheath is found in many, but not all, nerve fibers, both in the central and peripheral nervous systems.
Injury to a nerve affects the Neurilemma Sheath's ability to aid regeneration. Damage to the Myelin Sheath can severely disrupt nerve signal transmission.
The Neurilemma Sheath contains the nucleus of the Schwann cell. The Myelin Sheath is composed of compact layers of cell membrane but lacks a nucleus.
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Comparison Chart

Composition

Outer layer of Schwann cells
Layers of glial cell membrane

Function

Aids in nerve regeneration
Provides insulation, increases speed

Presence

All peripheral nerve fibers
Many nerve fibers in CNS and PNS

Role in Nerve Injury

Facilitates nerve healing
Disruption leads to signal transmission issues

Cellular Structure

Contains nucleus of Schwann cell
Lacks nucleus, made of compact layers

Compare with Definitions

Neurilemma Sheath

Schwann cell envelope around nerve fibers.
The Neurilemma Sheath facilitates communication in the nervous system.

Myelin Sheath

Protective coating made by glial cells.
Damage to the Myelin Sheath can cause neurological disorders.

Neurilemma Sheath

Essential component of the peripheral nervous system.
The Neurilemma Sheath surrounds and supports nerve fibers.

Myelin Sheath

Insulating layer around nerve fibers.
The Myelin Sheath enhances the speed of nerve impulses.

Neurilemma Sheath

Protective layer of Schwann cells on peripheral nerves.
The Neurilemma Sheath is crucial for peripheral nerve regeneration.

Myelin Sheath

Structure increasing neural conductivity.
The Myelin Sheath is essential for efficient brain function.

Neurilemma Sheath

Outermost layer surrounding a nerve fiber.
Injury to the Neurilemma Sheath can impact nerve repair.

Myelin Sheath

Glial cell wrapping around neurons.
Myelin Sheath disruptions are linked to multiple sclerosis.

Neurilemma Sheath

Schwann cell layer involved in nerve healing.
The Neurilemma Sheath’s presence aids in regrowth after nerve damage.

Myelin Sheath

Cellular layer facilitating rapid signal transmission.
The Myelin Sheath ensures quick response in the nervous system.

Common Curiosities

What is the Neurilemma Sheath?

It's the outermost layer of Schwann cells surrounding peripheral nerve fibers.

Can damage to the Neurilemma Sheath affect nerve repair?

Yes, damage to it can impede the nerve's ability to regenerate.

How do Neurilemma Sheath and Myelin Sheath differ in function?

The Neurilemma Sheath aids nerve regeneration; the Myelin Sheath provides insulation and increases impulse speed.

Are both sheaths present in the central nervous system?

The Myelin Sheath is present in both the CNS and PNS, but the Neurilemma Sheath is only in the PNS.

What is the Myelin Sheath?

It's an insulating layer formed by glial cells around nerve fibers.

What happens if the Myelin Sheath is damaged?

It can disrupt nerve signal transmission, leading to neurological issues.

Is the Neurilemma Sheath involved in nerve growth?

Yes, it plays a crucial role in nerve regeneration.

What cells contribute to the formation of the Myelin Sheath?

Oligodendrocytes in the CNS and Schwann cells in the PNS form the Myelin Sheath.

Are both sheaths important for the nervous system?

Yes, both play crucial roles in protecting and facilitating nerve function.

What cells form the Neurilemma Sheath?

Schwann cells form the Neurilemma Sheath.

Does the Neurilemma Sheath contain a nucleus?

Yes, it contains the nucleus of the Schwann cell.

What role does the Myelin Sheath play in nerve function?

It insulates nerve fibers, enhancing the speed and efficiency of impulse transmission.

Does the Myelin Sheath have a nucleus?

No, it's composed of compact layers of cell membrane without a nucleus.

Can the Neurilemma Sheath be found in all nerve fibers?

It's present in all peripheral nerve fibers.

Is the Myelin Sheath always present in nerve fibers?

It's present in many, but not all, nerve fibers in the CNS and PNS.

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Author Spotlight

Written by
Tayyaba Rehman
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to askdifference.com. As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.

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