Immunohistochemistry vs. Histopathology — What's the Difference?
Difference Between Immunohistochemistry and Histopathology
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Immunohistochemistry
Immunohistochemistry (IHC) is the most common application of immunostaining. It involves the process of selectively identifying antigens (proteins) in cells of a tissue section by exploiting the principle of antibodies binding specifically to antigens in biological tissues.
Histopathology
Histopathology (compound of three Greek words: ἱστός histos "tissue", πάθος pathos "suffering", and -λογία -logia "study of") refers to the microscopic examination of tissue in order to study the manifestations of disease. Specifically, in clinical medicine, histopathology refers to the examination of a biopsy or surgical specimen by a pathologist, after the specimen has been processed and histological sections have been placed onto glass slides.
Immunohistochemistry
The analytical process of finding proteins in cells of a tissue microtome section exploiting the principle of antibodies binding specifically to antigens in biological tissues.
Histopathology
The study of changes in tissues caused by disease.
Immunohistochemistry
An assay that shows specific antigens in tissues by the use of markers that are either fluorescent dyes or enzymes (such as horseradish peroxidase)
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Histopathology
The study of the microscopic anatomical changes in diseased tissue.
Histopathology
(biology) The microscopic study of tissue, especially of abnormal tissue as a result of disease.
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