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Genetic Code vs. Codon — What's the Difference?

Edited by Tayyaba Rehman — By Fiza Rafique — Published on December 23, 2023
Genetic Code is the set of rules by which DNA or mRNA is translated into proteins; Codon is a three-nucleotide sequence that codes for an amino acid or signals stop.
Genetic Code vs. Codon — What's the Difference?

Difference Between Genetic Code and Codon

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Key Differences

Genetic Code refers to the universal set of rules that governs how the information encoded within DNA or mRNA sequences is translated into proteins. Codon, on the other hand, specifically denotes the three-nucleotide sequence found in mRNA that represents a single amino acid or a stop signal in protein synthesis.
Genetic Code is the foundation upon which the entire process of protein synthesis is based. It determines how nucleotide sequences in the DNA or mRNA get converted into amino acid sequences in proteins. Meanwhile, the Codon serves as the fundamental unit of this code.
While the Genetic Code is consistent across nearly all organisms, implying its universality, every Codon is unique to a specific amino acid or serves as a punctuation mark to end translation.
To better understand, consider the Genetic Code as the language of life, stipulating how genes are read to form proteins. In this language, each Codon functions as a word, conveying specific information or command.
Although both the Genetic Code and Codon are intricately linked in the realm of molecular biology, they differ in their roles. The former is a broader concept, encapsulating the rules of translation, while the latter is a precise sequence dictating individual components of this translation process.
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Comparison Chart

Definition

Rules for translating nucleotide sequences to proteins
Three-nucleotide sequence in mRNA

Universality

Nearly universal across organisms
Specific sequences for each amino acid

Function

Governs protein synthesis
Represents individual amino acids

Level of Complexity

Broader concept
Smaller unit within the code

Example

Universal language of life
AUG codon codes for Methionine

Compare with Definitions

Genetic Code

Genetic Code is consistent across almost all known life forms.
The universality of the Genetic Code suggests a common ancestral origin for all life.

Codon

Codon dictates which amino acid will be added next in protein synthesis.
Each Codon in the mRNA corresponds to an amino acid in the protein.

Genetic Code

Genetic Code is a key component in the central dogma of biology.
Understanding the Genetic Code has been pivotal in advancing genetic research.

Codon

Codon is a three-nucleotide sequence in mRNA.
The AUG Codon signifies the start of translation.

Genetic Code

Genetic Code translates information from nucleotide sequences to amino acids.
Scientists have studied the Genetic Code to understand protein synthesis.

Codon

Codon can signal the end of protein synthesis.
The UAA, UAG, and UGA codons are stop signals in the Genetic Code.

Genetic Code

Genetic Code governs how DNA/RNA sequences produce protein chains.
Through the Genetic Code, our DNA determines our physical traits.

Codon

Codon is read by tRNA during translation.
TRNA molecules recognize and bind to specific Codons during protein synthesis.

Genetic Code

Genetic Code is the set of rules determining protein synthesis.
The Genetic Code dictates how genes are translated into proteins.

Codon

Codon serves as the word in the language of the Genetic Code.
Like words in a sentence, each Codon has a meaning in the protein synthesis process.

Codon

A sequence of three adjacent nucleotides constituting the genetic code that determines the insertion of a specific amino acid in a polypeptide chain during protein synthesis or the signal to stop protein synthesis.

Codon

A handbell used for summoning monks.

Codon

The "bell" or flaring mouth of a trumpet.

Codon

(biochemistry) A sequence of three adjacent nucleotides, which encode for a specific amino acid during protein synthesis or translation.

Codon

A sequence of three nucleotides in a genome or a DNA or messenger RNA molecule, which specifies the incorporation of one amino acid or is a stop signal, during the biosynthesis of proteins. Codons occur within the protein-coding segments of the DNA or RNA genome of living organisms. The amino acid sequence of proteins synthesized on ribosomes is thus determined by the sequence of the nucleotides in the genome.

Codon

A specific sequence of three adjacent bases on a strand of DNA or RNA that provides genetic code information for a particular amino acid

Common Curiosities

Are there Codons that don't code for amino acids?

Yes, there are stop Codons that signal the end of protein synthesis without coding for amino acids.

What is a Codon?

Codon is a specific three-nucleotide sequence in mRNA that represents an amino acid or stop signal.

How many nucleotides make up a Codon?

A Codon is composed of three nucleotides.

What molecule reads the Codons during translation?

tRNA molecules read and translate Codons into amino acids during protein synthesis.

How does the Genetic Code relate to Codons?

The Genetic Code utilizes Codons as units to determine which amino acids are added during protein synthesis.

Can a Codon represent more than one amino acid?

No, each Codon is specific to a single amino acid or serves as a stop signal.

Is the Genetic Code the same in all organisms?

The Genetic Code is nearly universal, with few exceptions, across all known organisms.

Is there any organism that doesn't use the standard Genetic Code?

While the Genetic Code is nearly universal, some organisms exhibit slight variations.

What is the Genetic Code?

Genetic Code is the set of rules by which DNA or mRNA sequences are translated into proteins.

What's the significance of the Genetic Code in biology?

The Genetic Code is fundamental to understanding how genetic information translates into functional proteins.

Do Codons exist in DNA or mRNA?

Codons are specific to mRNA, but the DNA sequence they originate from can be referred to as a codon sequence.

Why is the Genetic Code described as "degenerate"?

The Genetic Code is "degenerate" because multiple Codons can code for the same amino acid.

Can changes in a Codon impact an organism's traits?

Yes, changes or mutations in a Codon can alter protein function, potentially affecting the organism's traits.

How many possible Codons exist in the Genetic Code?

There are 64 possible Codons in the Genetic Code.

How did scientists decipher the Genetic Code?

Through biochemical experiments in the 1960s, scientists determined which Codons corresponded to which amino acids.

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Author Spotlight

Written by
Fiza Rafique
Fiza Rafique is a skilled content writer at AskDifference.com, where she meticulously refines and enhances written pieces. Drawing from her vast editorial expertise, Fiza ensures clarity, accuracy, and precision in every article. Passionate about language, she continually seeks to elevate the quality of content for readers worldwide.
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to askdifference.com. As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.

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