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Eukaryotic Cell vs. Prokaryotic Cell — What's the Difference?

By Tayyaba Rehman — Published on October 7, 2023
Eukaryotic cells have a nucleus and membrane-bound organelles; prokaryotic cells lack these structures.
Eukaryotic Cell vs. Prokaryotic Cell — What's the Difference?

Difference Between Eukaryotic Cell and Prokaryotic Cell

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Key Differences

Eukaryotic cells are characterized by the presence of a nucleus which houses the cell's DNA. In contrast, prokaryotic cells do not have a true nucleus; instead, their DNA floats freely within the cell.
Another distinguishing feature is the presence of membrane-bound organelles in eukaryotic cells, such as the mitochondria, Golgi apparatus, and endoplasmic reticulum. Prokaryotic cells lack these specialized structures.
Eukaryotic cells are generally larger and more complex than prokaryotic cells. While eukaryotic cells can form multicellular organisms like plants, animals, and fungi, prokaryotic cells are typically unicellular, like bacteria.
The cellular division is also different between the two. Eukaryotic cells divide through mitosis or meiosis, while prokaryotic cells reproduce through a process called binary fission.
In terms of evolution, eukaryotic cells are believed to have evolved later than prokaryotic cells, with the latter being one of the earliest forms of life on Earth.
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Comparison Chart

Presence of Nucleus

Contains a true nucleus with DNA.
No true nucleus; DNA floats freely.

Organelles

Has membrane-bound organelles.
Lacks membrane-bound organelles.

Size & Complexity

Generally larger and more complex.
Smaller and simpler.

Cell Division

Uses mitosis or meiosis.
Uses binary fission.

Evolutionary History

Evolved later, forming multicellular organisms.
Earlier life forms, typically unicellular.

Compare with Definitions

Eukaryotic Cell

A cell with a true nucleus.
Human cells are examples of eukaryotic cells.

Prokaryotic Cell

No membrane-bound organelles.
The DNA in a prokaryotic cell is not contained within a nucleus.

Eukaryotic Cell

Forms multicellular organisms.
Plants are composed of eukaryotic cells.

Prokaryotic Cell

Divides via binary fission.
When a prokaryotic cell reproduces, it splits into two.

Eukaryotic Cell

Contains membrane-bound organelles.
The mitochondria in a eukaryotic cell produce ATP.

Prokaryotic Cell

Typically unicellular organisms.
E. coli is a type of prokaryotic cell.

Eukaryotic Cell

Divides via mitosis or meiosis.
During reproduction, a eukaryotic cell can undergo meiosis.

Prokaryotic Cell

Represents primitive cellular evolution.
Prokaryotic cells are some of the earliest life forms on Earth.

Eukaryotic Cell

Represents advanced cellular evolution.
Fungi are formed from eukaryotic cells.

Prokaryotic Cell

A cell lacking a true nucleus.
Bacteria are examples of prokaryotic cells.

Common Curiosities

Are prokaryotic cells more complex than eukaryotic cells?

No, prokaryotic cells are simpler and lack many structures found in eukaryotic cells.

Which cell type has membrane-bound organelles?

Eukaryotic cells have membrane-bound organelles.

How do prokaryotic cells reproduce?

Prokaryotic cells reproduce via binary fission.

Are humans made of prokaryotic or eukaryotic cells?

Humans are made of eukaryotic cells.

How do eukaryotic cells divide?

Eukaryotic cells divide through mitosis or meiosis.

Which cell type is typically multicellular?

Eukaryotic cells can form multicellular organisms.

Do eukaryotic cells have a true nucleus?

Yes, eukaryotic cells have a true nucleus containing DNA.

Which cell type is larger in size?

Eukaryotic cells are generally larger than prokaryotic cells.

Do prokaryotic cells have mitochondria?

No, prokaryotic cells lack mitochondria.

What organisms are primarily made of prokaryotic cells?

Bacteria and archaea are primarily made of prokaryotic cells.

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Author Spotlight

Written by
Tayyaba Rehman
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to askdifference.com. As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.

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