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RBC vs. WBC — What's the Difference?

By Tayyaba Rehman — Updated on September 23, 2023
RBC (Red Blood Cell) transports oxygen in the blood; WBC (White Blood Cell) defends against infections.
RBC vs. WBC — What's the Difference?

Difference Between RBC and WBC

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Key Differences

RBCs, or Red Blood Cells, predominantly function to deliver oxygen to body tissues. Their biconcave shape enhances their oxygen-carrying capacity. WBCs, or White Blood Cells, have a completely different role as they primarily deal with the body's immune response, fighting off infections and foreign invaders.
The quantity of RBCs typically surpasses that of WBCs in the human body. A drop of blood contains millions of RBCs compared to thousands of WBCs. While the former ensures tissues receive adequate oxygen, the latter remain fewer in number but rapidly increase when facing infections.
RBCs contain a red pigment called hemoglobin, enabling them to transport oxygen. WBCs lack this pigment, making them appear transparent. While RBCs are focused on oxygenation, WBCs come in various types, each tailored to tackle different pathogens or threats.
The lifespan of an RBC is relatively short, averaging about 120 days. Once aged, they're removed by the spleen. WBCs, on the other hand, can vary in lifespan. Some exist for only hours, while others can persist for years, depending on their type and function.
Finally, the formation of RBCs, known as erythropoiesis, occurs in the bone marrow. WBCs, too, originate in the bone marrow but can further mat
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Comparison Chart

Primary Function

Transports oxygen to body tissues.
Defends against infections and foreign invaders.

Count in Blood

Millions in a drop of blood.
Thousands in a drop of blood.

Pigment

Contains red pigment (hemoglobin).
Lacks pigment, appears transparent.

Lifespan

Around 120 days.
Ranges from hours to years, depending on type.

Formation Place

Primarily in the bone marrow.
Originates in the bone marrow but may mature elsewhere.

Compare with Definitions

Rbc

Possesses a biconcave shape to enhance surface area.
The unique shape of the RBC aids in its oxygen-carrying function.

Wbc

Comes in various forms, including neutrophils and lymphocytes.
Different types of WBCs respond to different types of infections.

Rbc

A cell that carries oxygen throughout the body.
The high altitude training increased his RBC count.

Wbc

Lacks hemoglobin and appears transparent under a microscope.
Unlike the RBC, the WBC doesn't carry oxygen.

Rbc

Known for its distinctive red color due to hemoglobin.
The presence of hemoglobin gives the RBC its red color.

Wbc

Produced in the bone marrow and can mature in other sites.
Some WBCs, like T-cells, mature in the thymus.

Rbc

Essential for transporting carbon dioxide away from tissues.
The RBC picks up carbon dioxide, a waste product, from body tissues.

Wbc

A cell that combats infections and foreign invaders.
When an infection arises, the WBC count typically goes up.

Rbc

Produced in the bone marrow through erythropoiesis.
The rate of RBC production increases when oxygen levels are low.

Wbc

Integral component of the body's immune system.
A low WBC count can indicate a weakened immune system.

Rbc

A mature blood cell that contains hemoglobin to carry oxygen to the bodily tissues; a biconcave disc that has no nucleus

Wbc

Blood cells that engulf and digest bacteria and fungi; an important part of the body's defense system

Common Curiosities

What's the main role of WBCs?

WBCs mainly defend the body against infections and foreign invaders.

Do both RBCs and WBCs contain hemoglobin?

Only RBCs contain hemoglobin, giving them their red color.

Why is the shape of the RBC significant?

Its biconcave shape maximizes surface area for oxygen binding.

What's the main role of RBCs?

RBCs primarily transport oxygen to body tissues.

How do RBCs and WBCs differ visually?

RBCs are red due to hemoglobin, while WBCs are transparent.

Where are these cells produced?

Both RBCs and WBCs originate in the bone marrow, but WBCs might mature elsewhere.

Which blood cell is more numerous?

RBCs are more numerous than WBCs in the bloodstream.

Why might a doctor monitor WBC count?

To gauge the body's response to infection or to assess immune health.

What happens to old RBCs?

They are removed by organs like the spleen after about 120 days.

Can WBC count increase suddenly?

Yes, especially during infections or inflammation.

Are there different types of WBCs?

Yes, including neutrophils, lymphocytes, and macrophages, among others.

Can a person survive with low RBC or WBC counts?

It depends on the severity; both low RBC and WBC counts can be life-threatening if extreme.

Why might someone need an RBC transfusion?

Due to conditions like anemia, surgery, or significant blood loss.

What diseases can affect WBCs?

Leukemia, HIV/AIDS, and bone marrow disorders can affect WBC counts.

How do RBCs carry waste like carbon dioxide?

They bind to carbon dioxide, transporting it away from tissues.

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Author Spotlight

Written by
Tayyaba Rehman
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to askdifference.com. As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.

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