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Granulocytes vs. Agranulocytes — What's the Difference?

By Tayyaba Rehman — Published on November 29, 2023
Granulocytes are white blood cells with granules in their cytoplasm, while Agranulocytes lack these visible granules.
Granulocytes vs. Agranulocytes — What's the Difference?

Difference Between Granulocytes and Agranulocytes

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Key Differences

Granulocytes and Agranulocytes are both types of white blood cells, playing vital roles in the immune system.
Tayyaba Rehman
Nov 29, 2023
Granulocytes contain noticeable granules in their cytoplasm, which are filled with enzymes that play roles in the cell's function. Agranulocytes, in contrast, do not contain these prominent granules.
Tayyaba Rehman
Nov 29, 2023
Granulocytes can be further divided into three main types based on their staining properties.
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Nov 29, 2023
These are neutrophils, eosinophils, and basophils. Agranulocytes, on the other hand, mainly comprise lymphocytes and monocytes.
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Nov 29, 2023
Both Granulocytes and Agranulocytes function in the body's defense against pathogens.
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Nov 29, 2023
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Granulocytes often engage in phagocytosis, where they engulf and digest pathogens. Agranulocytes, especially lymphocytes, have roles in antibody production, immune response regulation, and also direct cellular attacks on pathogens.
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Nov 29, 2023
The presence or absence of granules is the primary distinguishing factor.
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Nov 29, 2023
In Granulocytes, these granules contain enzymes and other substances crucial for the cell to carry out its immune functions. Agranulocytes lack these characteristic granules but have other specialized functions in the immune system.
Tayyaba Rehman
Nov 29, 2023

Comparison Chart

Granule Presence

Contain noticeable granules in their cytoplasm
Lack prominent granules
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Nov 29, 2023

Main Types

Neutrophils, eosinophils, basophils
Lymphocytes, monocytes
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Nov 29, 2023

Primary Function

Often engage in phagocytosis
Involved in antibody production, immune regulation
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Nov 29, 2023

Cytoplasm Appearance

Granular
Smooth
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Immune Role

Direct defense against pathogens
Both direct and regulatory roles in immunity
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Nov 29, 2023

Compare with Definitions

Granulocytes

Immune cells primarily involved in the defense against bacterial infections.
A decline in granulocytes can make an individual more susceptible to bacterial infections.
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Oct 11, 2023

Agranulocytes

White blood cells lacking visible granules in their cytoplasm.
Agranulocytes play essential roles in modulating the immune response.
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Oct 11, 2023

Granulocytes

Leukocytes categorized based on their staining properties and granular cytoplasm.
There's an increase in certain granulocytes during specific infections.
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Oct 11, 2023

Agranulocytes

Immune cells that include lymphocytes and monocytes.
Agranulocytes are vital for both immediate and long-term immunity.
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Oct 11, 2023

Granulocytes

White blood cells with prominent granules in their cytoplasm.
Granulocytes are crucial for the immediate response to infections.
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Oct 11, 2023

Agranulocytes

Immune cells that regulate and support the immune system's response to pathogens.
The two main types of agranulocytes have distinct roles in protecting the body.
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Oct 11, 2023

Granulocytes

Cells that often engage in engulfing and digesting pathogens.
Granulocytes quickly move to the site of infection to neutralize threats.
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Oct 11, 2023

Agranulocytes

Cells primarily involved in adaptive immune responses.
Agranulocytes, especially lymphocytes, recognize and remember pathogens for future encounters.
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Oct 11, 2023

Granulocytes

Cells named for their granular appearance under a microscope after staining.
Granulocytes can be differentiated based on how they stain with certain dyes.
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Oct 11, 2023

Agranulocytes

Leukocytes with a smooth appearance under a microscope.
Agranulocytes can be distinguished from granulocytes by their lack of granules.
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Oct 11, 2023

Granulocytes

Any of a group of white blood cells having granules in the cytoplasm. Neutrophils, eosinophils, and basophils are granulocytes.
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Oct 06, 2023

Agranulocytes

Plural of agranulocyte
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Oct 06, 2023

Granulocytes

Plural of granulocyte
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Oct 06, 2023

Common Curiosities

Are both Granulocytes and Agranulocytes white blood cells?

Yes, both are types of white blood cells.
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Nov 29, 2023

Can Granulocytes produce antibodies?

No, antibody production is a function of lymphocytes, a type of Agranulocyte.
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Nov 29, 2023

Are the granules in Granulocytes visible without staining?

The granules are best observed under a microscope after staining.
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Do Agranulocytes participate in phagocytosis?

While some agranulocytes, like monocytes, can engage in phagocytosis, lymphocytes primarily do not.
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Nov 29, 2023

Which cell type is more prevalent in the blood, Granulocytes or Agranulocytes?

Granulocytes, especially neutrophils, are more numerous in the blood under normal conditions.
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Nov 29, 2023

Which type of cell responds to viral infections?

Both can respond, but lymphocytes (Agranulocytes) play a key role in viral infections.
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Nov 29, 2023

Why are Granulocytes called polymorphonuclear cells?

Because of their varied and multi-lobed nuclear shapes.
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What gives Granulocytes their granular appearance?

They contain noticeable granules in their cytoplasm filled with enzymes.
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Nov 29, 2023

Do Granulocytes have a role in inflammation?

Yes, especially neutrophils and basophils, which are Granulocytes, play roles in the inflammatory process.
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Nov 29, 2023

Which has a longer lifespan, Granulocytes or Agranulocytes?

Agranulocytes, particularly some lymphocytes, have a longer lifespan than most Granulocytes.
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Nov 29, 2023

Are all Granulocytes alike?

No, there are different types of Granulocytes, such as neutrophils, eosinophils, and basophils, each with specific functions.
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Nov 29, 2023

Do Agranulocytes have any granules at all?

Agranulocytes might have tiny granules, but they're not as prominent or functionally significant as those in Granulocytes.
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Nov 29, 2023

Are Agranulocytes involved in the body's long-term immunity?

Yes, lymphocytes, a type of Agranulocyte, play a central role in long-term and memory-based immunity.
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Nov 29, 2023

How can I differentiate between Granulocytes and Agranulocytes in a blood sample?

Under a microscope, after staining, Granulocytes will appear granular, while Agranulocytes will have a smoother appearance.
Tayyaba Rehman
Nov 29, 2023

Which cells play a role in allergic reactions?

Eosinophils and basophils, both types of Granulocytes, are involved in allergic responses.
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Nov 29, 2023

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Author Spotlight

Written by
Tayyaba Rehman
Tayyaba Rehman is a distinguished writer, currently serving as a primary contributor to askdifference.com. As a researcher in semantics and etymology, Tayyaba's passion for the complexity of languages and their distinctions has found a perfect home on the platform. Tayyaba delves into the intricacies of language, distinguishing between commonly confused words and phrases, thereby providing clarity for readers worldwide.

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