Fosaprepitant vs. Aprepitant — What's the Difference?

Fosaprepitant (Emend for Injection (US), Ivemend (EU)) is an antiemetic medication, administered intravenously. It is a prodrug of aprepitant.

Aprepitant, sold under the brand name Emend among others, is a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. It may be used together with ondansetron and dexamethasone.

(pharmaceutical drug) A prodrug of aprepitant, administered intravenously as an antiemetic.

(pharmaceutical drug) An antiemetic drug C₂₃H₂₁F₇N₄O₃ taken orally to prevent nausea and vomiting occurring as a consequence of cancer chemotherapy or surgery. It acts as an antagonist of receptors for substance P. It is often taken in combination with other antiemetic drugs and is marketed under the trademark Emend.