VS.

Cadherin vs. Integrin

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Cadherinnoun

(protein) Any of a class of transmembrane proteins important in maintaining tissue structure.

Integrinnoun

(biochemistry) Any of many heterodimeric transmembrane proteins that function as receptors in communication between cells.

Cadherin

Cadherins (named for ) are a type of cell adhesion molecule (CAM) that are important in the formation of adherens junctions to allow cells to adhere to each other . Cadherins are a class of type-1 transmembrane proteins, and they are dependent on calcium (Ca2+) ions to function, hence their name.

‘calcium-dependent adhesion’;

Integrin

Integrins are transmembrane receptors that facilitate cell-cell and cell-extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal transduction pathways that mediate cellular signals such as regulation of the cell cycle, organization of the intracellular cytoskeleton, and movement of new receptors to the cell membrane.

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