Biomolecule vs. Macromolecule — What's the Difference?

A biomolecule or biological molecule is a loosely used term for molecules present in organisms that are essential to one or more typically biological processes, such as cell division, morphogenesis, or development. Biomolecules include large macromolecules (or polyanions) such as proteins, carbohydrates, lipids, and nucleic acids, as well as small molecules such as primary metabolites, secondary metabolites and natural products.

A macromolecule is a very large molecule, such as a protein. They are composed of thousands of covalently bonded atoms.

(biochemistry) molecules, such as amino acids, sugars, nucleic acids, proteins, polysaccharides, DNA, and RNA, that occur naturally in living organisms

A very large molecule, such as a polymer or protein, consisting of many smaller structural units linked together. Also called supermolecule.

A very large molecule, especially used in reference to large biological polymers (e.g. nucleic acids and proteins).

A very large molecule, especially a polymer having from hundreds to many thousands of atoms, such as DNA, RNA, protein, polysaccharide, polyethylene, polycarbonate, etc.

Any very large complex molecule; found only in plants and animals